Bioinorganic and Coordination Chemistry
Bioinorganic Chemistry
The bioinorganic chemistry group conducts work in fundamental bioinorganic chemistry and the development of novel drugs, organometallic anticancer agents, and novel cobalt-based coordination polymers.
- Dr Sadhna Mathura | Sadhna.mathura@wits.ac.za |
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The Mathura Biochrome Research Group (MBRG) is dedicated to advancing the field of bioinorganic chemistry, with a specialised focus on the structural and functional complexities of biological chromophores (biochromes). MBRG explores a diverse array of biochromes such as anthocyanins and carotenoids, however our primary emphasis lies in examining the versatility of tetrapyrroles. Tetrapyrroles range from macrocyclic frameworks like porphyrins and corrins to more linear architectures such as the bilirubins (and their smaller building blocks). We are especially curious about their interactions with metal ions. Beyond our intrinsic fascination with these systems, our work is motivated by the idea that these colourful natural systems hold the key to the next generation of sustainable technologies (e.g. enduring therapeutic design, metal chelators and biosensors). By translating the elegance of natural chemical systems into bio-inspired technologies, the multi-disciplinary MBRG team strives to provide innovative solutions to global challenges. The bioinorganic chemistry group conducts work in fundamental bioinorganic chemistry and the development of novel drugs, organometallic anticancer agents, and novel cobalt-based coordination polymers. |
- Dr Monika Nowakowska | Monika.Nowakowska@wits.ac.za |
- Prof. Helder Marques | Helder.marques@wits.ac.za |
Coordination Chemistry
Work in Coordination Chemistry focuses on the development and modification of catalysts for olefin oligomerization and polymerization, carbon-carbon coupling reactions, hydroformylation, and development of recyclable catalysts for the synthesis of biodegradable polymers.
- Dr Izak Kotzé | Izak.kotze@wits.ac.za |
- Dr Juanita van Wyk | Juanita.vanwyk@wits.ac.za |
